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Thursday, April 14, 2011

Lichen Planus and Eyes

Isolated lichen planus of the conjunctiva





Abstract:
 
Lichen planus is an autoimmune condition of unknown aetiology affecting the skin and mucous membranes. 

Classic lesions appear as recurrent, small, discrete, polygonal, flat topped, violaceous, pruritic papules distributed symmetrically on the flexor surfaces of the extremities and trunk. 

These lesions are often accompanied by lesions of the oral, genital, and rarely, ocular mucosa. 

Conjunctival lichen planus can lead to irreversible damage to the ocular surface and loss of vision from corneal scarring.

We report two patients with isolated lichen planus of the conjunctiva. 

The referring ophthalmologists had attributed these ocular findings to a severe dry eye state. 

The correct diagnosis was made by conjunctival biopsy.

Treatment with topical ciclosporin A resulted in suppression of the inflammation and arrest of the progressive cicatrisation. 

From:
British Journal of Ophthalmology  
2006;90:1325-1326  
doi:10.1136/bjo.2006.096263
  1. M Pakravan,
  2. T R Klesert,
  3. E K Akpek
+ Author Affiliations
  1. The Ocular Surface Diseases and Dry Eye Clinic, The Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA

Correspondence to:
Esen Karamursel Akpek MD, Director 
Ocular Surface Diseases and Dry Eye Clinic
The Wilmer Eye Institute
600 North Wolfe Street
Maumenee Building No 321
Baltimore, MD 21287-9238, USA




2 comments:

Enjoy The Present said...

Informative post, thanks for sharing. It's particularly interesting because I've noticed my eyes burning since acquiring my condition (possible OLP). I don't know if they're related but it's worth taking note.

I've been reading through your blog and was wondering if you could get a hold of me about a health insurance question regarding OLP, or if so inclined can we discuss it here? Appreciate any feedback. takeadeepbreath75(at)gmail.com

Elizabeth Munroz said...

Thank you for leaving your comment. I hope you don't have OLP. But, if you do, I hope yours will resolve quickly.

Thanks for leaving your email addy. Will get in touch with you.



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