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Monday, April 11, 2011

Do Medications cause Oral Lichen Planus?


Abstract
Objectives: To investigate whether daily systemic and/or topical medication contributes to the development of oral
lichen planus (OLP) lesions.

Study Design:
The study involved 110 OLP patients and 76 control subjects, matched by age, race and sex. The analyzed data included medical records, drug intake and topical medication.

Results:
No statistical difference was found between the two groups in terms of systemic diseases, number of medicated individuals in the categories of mono- and polypharmacy,

Regarding the clinical forms and site of involvement, a statistically significant difference was only found for the clinical erosive form of OLP

Conclusions:
It seems that the use of systemic medication does not lead to a significant increase in the incidence of OLP lesions. For their part, lichenoid drug reactions are likely to occur only in a very low percentage of patients.

Please note: I have paraphrased this abstract. To see the complete article, go here.

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