Monday, April 11, 2011
Do Medications cause Oral Lichen Planus?
Objectives: To investigate whether daily systemic and/or topical medication contributes to the development of oral
lichen planus (OLP) lesions.
The study involved 110 OLP patients and 76 control subjects, matched by age, race and sex. The analyzed data included medical records, drug intake and topical medication.
No statistical difference was found between the two groups in terms of systemic diseases, number of medicated individuals in the categories of mono- and polypharmacy,
Regarding the clinical forms and site of involvement, a statistically significant difference was only found for the clinical erosive form of OLP
It seems that the use of systemic medication does not lead to a significant increase in the incidence of OLP lesions. For their part, lichenoid drug reactions are likely to occur only in a very low percentage of patients.
Please note: I have paraphrased this abstract. To see the complete article, go here.
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