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Friday, April 1, 2011

674 patients with oral lichen planus

These are notes from an abstract to see the full abstract go here.

Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical presentations that can be classified as:

reticular
atrophic
erosive

Although OLP is a relatively common disorder, the reports comprising large numbers of OLP patients with specific character are lacking in the literature. 

Of the 674 patients, 65% were women and 34% were men. The most common clinical presentation was the reticular type, and symptomatic OLP was noted in 67% of the patients, mainly in those with the erosive form. 

The erosive presentations showed significantly longer duration, more sites affected and a much greater older patients predominance than reticular or atrophic ones.

No statistically significant differences could be identified between OLP and diabetes, cardiovascular disease, smoking or alcohol use. 

Precipitating factors that resulted in an exacerbation of the disease were frequently noted and included: 


foods
stress
dental cusp (biting surfaces of the teeth)
poor oral hygiene. 

The transformation of OLP into malignancy was observed in four patients at sites previously diagnosed by clinical examination as erosive or atrophic lichen planus.

A long time follow up is of utmost importance to detect its malignant transformation.

From: 
 

A clinical study of 674 patients with oral lichen planus in China.

Journal of Oral Pathol Med. 2005 Sep;34(8):467-72.

Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L.

Source

Key Lab for Oral Biochemical Engineering 
Ministry of Education, 
Stomatological College of Wuhan University, 
Luoyu Road 65, 430079 Wuhan, Hubei, China.
PMID:
16091113
[PubMed - indexed for MEDLINE]

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