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Tuesday, January 11, 2011

Laser Versus Topical in Oral Lichen Planus



A Comparative Pilot Study of Low Intensity Laser versus Topical Corticosteroids in the Treatment of Erosive-Atrophic Oral Lichen Planus


Abstract

Background and objective:
Treatment of oral lichen planus (OLP) remains a great challenge for clinicians. The aim of our study was to compare the effect of low intensity laser therapy (LILT) with topical corticosteroids in the treatment of oral erosive and atrophic lichen planus.

Materials and Methods:
Thirty patients with erosive-atrophic OLP were randomly allocated into two groups.

The experimental group consisted of patients treated with the 630nm diode laser. The control group consisted of patients who used Dexamethason mouth wash.

Response rate was defined based on changes in the appearance score and pain score (Visual Analogue Scale) of the lesions before and after each treatment.

Results:
Appearance score, pain score, and lesion severity was reduced in both groups. No significant differences were found between the treatment groups regarding the response rate and relapse.

Conclusion:
Our study demonstrated that LILT was as effective as topical corticosteroid therapy without any adverse effects and it may be considered as an alternative treatment for erosive-atrophic OLP in the future.

From:
Photomedicine and Laser Surgery

A Comparative Pilot Study of Low Intensity Laser versus Topical Corticosteroids in the Treatment of Erosive-Atrophic Oral Lichen Planus

Hasan Hoseinpour Jajarm, D.D.S., M.Sc.,1
Farnaz Falaki, D.D.S., M.Sc.,1 and
Omid Mahdavi, D.D.S., M.Sc.2
1Department of Oral Medicine and Dental Research Center,
Faculty of Dentistry,
Mashhad, Iran.

2Department of Oral Medicine and Dental Research Center,
Faculty of Dentistry,
Yazd, Iran.

Address correspondence to:
Dr. Farnaz Falaki
Department of Oral Medicine
Faculty of Dentistry and Dental, Research Center
Mashhad University of Medical Sciences
P.O. Box 91735-984
Mashhad
Iran
E-mail: farnazfalaki@yahoo.com

Online Ahead of Print: January 8, 2011

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