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Sunday, November 7, 2010

Esophageal Lichen Planus Abstract 2

Esophageal lichen planus is an under-recognized condition, with fewer than 50 cases reported to date.

Unlike cutaneous lichen planus, esophageal lichen planus occurs almost exclusively in middle-aged or older women who also have oral involvement.

It commonly involves the proximal esophagus and manifests as progressive dysphagia and odynophagia.

Endoscopic findings can include lacy white papules, pinpoint erosions, desquamation, pseudomembranes, and stenosis.

Histologic features of esophageal lichen planus have only rarely been illustrated. They differ from those of cutaneous disease in several respects, including the presence of parakeratosis, epithelial atrophy, and lack of hypergranulosis.

Correct diagnosis of esophageal lichen planus is difficult but bears important therapeutic implications. It is typically a chronic and relapsing condition that can require systemic or local immunosuppressive therapy and repeated endoscopic dilatations for esophageal strictures.

Esophageal lichen planus may have malignant potential, as evidenced by 3 patients who developed squamous carcinoma of the esophagus after longstanding disease.


Note: This abstract is from these sources:


Arch Pathol Lab Med. 2008 Jun;132(6):1026-9.
Esophageal lichen planus.

Chandan VS,
Murray JA,
Abraham SC.

Division of Anatomic Pathology,
Mayo Clinic,
Rochester, MN 55905, USA.

Abstract

PMID: 18517264 [PubMed - indexed for MEDLINE]

1 comment:

Anonymous said...

I have lichen planus in the esophagus and have been struggling with treatment. I would like to connect with anyone with this condition.



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