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Saturday, October 23, 2010

Esophageal Lichen Planus Abstract

Esophageal lichen planus is a rare condition, and although the majority of cases occur in conjunction with lichen planus at other sites, the endoscopic features are often misinterpreted resulting in a delay in diagnosis.

We report a series of five patients presenting to our unit between 2005 and 2009. All five patients were female and presented with dysphagia.

Endoscopy demonstrated proximal esophageal stricturing in four patients.

Characteristic histological findings were found in four patients.

Lichen planus was diagnosed at other sites, and preceded gastrointestinal symptoms, in all patients; five had oral involvement, two had genital involvement, and one had dermal involvement.

All patients received proton pump inhibitor therapy without demonstrable benefit.

Administration of oral fluticasone proprionate resulted in symptomatic improvement in three patients.

Note: this abstract is from the following sources



Dis Esophagus. 2010 Oct 13. doi: 10.1111/j.1442-2050.2010.01120.x. [Epub ahead of print]

Fluticasone propionate for treatment of esophageal lichen planus. A case series.

Donnellan F, Swan MP, May GR, Kandel G, Marcon NE, Kortan PP.

Centre for Therapeutic Endoscopy and Endoscopic Oncology, St. Michael's Hospital, Toronto, Canada.




© 2010 Copyright the Authors. Journal compilation © 2010, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.

PMID: 20946136 [PubMed - as supplied by publisher]

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